Pharmacognosy Research

ORIGINAL ARTICLE
Year
: 2015  |  Volume : 7  |  Issue : 1  |  Page : 81--84

Evaluation of Bacillus cereus and Bacillus pumilus metabolites for anthelmintic activity


ML Vijaya Kumar1, B Thippeswamy2, IL Kuppust1, KJ Naveenkumar2, CK Shivakumar2 
1 Department of Pharmacognosy, National College of Pharmacy, Shankarghatta, Shimoga, Karnataka, India
2 Department of Microbiology, Kuvempu University, Shankarghatta, Shimoga, Karnataka, India

Correspondence Address:
Dr. B Thippeswamy
Department of Microbiology, Kuvempu University, Shankarghatta, Shimoga, Karnataka
India

Objective: To assess the anthelmintic acivity of Bacillus cereus and Bacillus pumilus metabolites. Materials and Methods: The successive solvent extractions with petroleum ether, ethyl acetate and methanol. The solvent extracts were tested for anthelmintic activity against Pheretima posthuma at 20 mg/ml concentration. The time of paralysis and time of death of the worms was determined for all the extracts. Albendazole was taken as a standard reference and sterile water as a control. Results: All the sample extracts showed significant anthelmintic activity in paralyzing the worms comparable with that of the standard drug. The time of death exhibited by BP metabolites was close to the time exhibited by standard. Conclusion: The study indicates both bacteria Bacillus cereus and Bacillus pumilus have anthelmintic activity indicating potential metabolites in them.


How to cite this article:
Vijaya Kumar M L, Thippeswamy B, Kuppust I L, Naveenkumar K J, Shivakumar C K. Evaluation of Bacillus cereus and Bacillus pumilus metabolites for anthelmintic activity.Phcog Res 2015;7:81-84


How to cite this URL:
Vijaya Kumar M L, Thippeswamy B, Kuppust I L, Naveenkumar K J, Shivakumar C K. Evaluation of Bacillus cereus and Bacillus pumilus metabolites for anthelmintic activity. Phcog Res [serial online] 2015 [cited 2020 May 25 ];7:81-84
Available from: http://www.phcogres.com/article.asp?issn=0974-8490;year=2015;volume=7;issue=1;spage=81;epage=84;aulast=Vijaya;type=0