Pharmacognosy Research

ORIGINAL ARTICLE
Year
: 2010  |  Volume : 2  |  Issue : 3  |  Page : 169--174

Effect of Celastrus paniculatus seed oil (Jyothismati oil) on acute and chronic immobilization stress induced in swiss albino mice


George Lekha1, Karthik Mohan2, Irudhaya Arockia Samy3 
1 Department of Botany, Mount Carmel College, Bangalore, Karnataka, India
2 Department of Biochemistry, St. Joseph's College (Autonomous), Trichy, Tamil Nadu, India
3 Department of Plant Biology and Plant Biotechnology, St. Joseph's College (Autonomous), Trichy, Tamil Nadu, India

Correspondence Address:
Karthik Mohan
Department of Biochemistry, St. Joseph«SQ»s College, Trichy, Tamil Nadu
India

Stress alters the homeostasis and is produced by several factors. Immobilization stress induced due to reduced floor area provided for the mobility results in the imbalance of oxidant and antioxidant status. The modern computer savvy world decreases human mobility in the working environment, leading to the formation of oxygen free radicals and if left untreated might result in severe health problems like hypertension, cardiovascular disease, premature aging and brain dysfunction. Hence, modern medicines rely upon the medicinal plants for some drugs with zero side effects. In this context, Jyothismati oil (JO), extracted from Celastrus paniculatus seeds, was used to treat acute and chronic immobilization induced experimentally. C. paniculatus plant is considered to be rich in antioxidant content and so the seed oil extract«SQ»s efficacy was tested against immobilization stress in albino mice. The animals were kept in a restrainer for short and long durations, grouped separately and fed with the drug. Animals were sacrificed and the samples were analyzed. The antioxidant enzyme levels of the animals regained and markedly increased in the acute and chronic immobilized groups, respectively. The results suggested that the extract of C. paniculatus seed was highly efficacious in reducing the stress induced by least mobility for hours.


How to cite this article:
Lekha G, Mohan K, Samy IA. Effect of Celastrus paniculatus seed oil (Jyothismati oil) on acute and chronic immobilization stress induced in swiss albino mice.Phcog Res 2010;2:169-174


How to cite this URL:
Lekha G, Mohan K, Samy IA. Effect of Celastrus paniculatus seed oil (Jyothismati oil) on acute and chronic immobilization stress induced in swiss albino mice. Phcog Res [serial online] 2010 [cited 2020 Sep 21 ];2:169-174
Available from: http://www.phcogres.com/article.asp?issn=0974-8490;year=2010;volume=2;issue=3;spage=169;epage=174;aulast=Lekha;type=0