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ORIGINAL ARTICLE
Year : 2015  |  Volume : 7  |  Issue : 1  |  Page : 14-17

Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia


1 Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt
2 Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt; Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia
3 University of Münster, Institute of Pharmaceutical Biology and Phytochemistry, Hittorfstraße 56, D 48149 Münster, Germany

Correspondence Address:
Dina Abou-Hussein
Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-8490.147136

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Investigation of the chloroform extract of Euphorbia ammak leaves led to the isolation of three compounds: euphol (1), α-glutinol (2) and stigmasterol (3) Their structures were elucidated by 1D and 2D NMR, as well as by comparison with the reported data. Compounds 1-3 exhibited cytotoxicity in vitro against human cervical adenocarcinoma (Hela), among which, compound 1 showed the best activity.


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