Home | About PR | Editorial board | Search | Ahead of print | Current Issue | Archives | Instructions | Subscribe | Advertise | Contact us |   Login 
Pharmacognosy Magazine
Search Article 
  
Advanced search 
 
SHORT COMMUNICATION
Year : 2012  |  Volume : 4  |  Issue : 2  |  Page : 123-126

In vitro H + -K + ATPase inhibitory potential of methanolic extract of Cissus quadrangularis Linn.


1 Department of Pharmacology, Shri Ram Institute of Technology -Pharmacy, Jabalpur, Madhya Pradesh, India
2 Department of Pharmacy, Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur, Madhya Pradesh, India

Correspondence Address:
Gopal Rai
Department of Pharmacy, Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur, Madhya Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-8490.94738

Rights and Permissions

Objective: This study was undertaken to study in vitro H + -K + ATPase inhibitory potential of methanolic extract of Cissus quadrangularis Linn. Materials and Methods: Total phenolic and flavonoid contents from extract was quantified and H + -K + ATPase inhibition assay was performed in presence of different concentrations of standard (omeprazole) and methanol extract. Results: Extract showed significant (*P < 0.05) proton pump inhibitory activity in the goat gastric mucosal homogenate which was comparable to standard. Conclusions: These findings showed that methanolic extract of C. quadrangularis Linn. is potent inhibitor of proton pump.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1997    
    Printed121    
    Emailed2    
    PDF Downloaded21    
    Comments [Add]    
    Cited by others 3    

Recommend this journal