Home | About PR | Editorial board | Search | Ahead of print | Current Issue | Archives | Instructions | Subscribe | Advertise | Contact us |   Login 
Pharmacognosy Magazine
Search Article 
Advanced search 
Year : 2011  |  Volume : 3  |  Issue : 3  |  Page : 151-154

Isolation and identification of a new flavonoid glycoside from Carrichtera annua L. seeds

1 Department of Phytochemistry, National Research Center, Dokki, Cairo, Egypt
2 Department of Phytochemistry, National Research Center, Dokki, Cairo, Egypt; Department of Chemistry, Sirt University, Sirt, Libya
3 Department of Pharmacognosy, College of Pharmacy, Misr University of Science and Technology (MUST), 6th of October City, Egypt

Correspondence Address:
Abdelaaty A Shahat
Department of Phytochemistry, National Research Centre, Bohouth Street, 12311 Dokki, Giza, Egypt

Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-8490.84998

Rights and Permissions

Background: Flavonoids are a major group of constituents and are assumed to be among the beneficial components. Recently, they have also received considerable interest as components of foodstuffs and nutraceuticals because of their antioxidant and anticancer properties. Materials and Methods: About 500 g of air-dried powdered seeds of C. annua were defatted seeds and extracted with 70% methanol. The combined methanol extract was partitioned with chloroform and n-butanol. The butanol extract was concentrated and subjected to column chromatography on polyamide. Results: The fraction eluted with aqueous methanol (40% and 50%) was found to contain three main flavonoids (1, 2, and 3). Repeated column chromatography on polyamide and Sephadex LH-20 gave compound 1. Compounds 2 and 3 were further purified using preparative paper chromatography with 20% HOAc and Sephadex LH-20 column. Conclusions: Reinvestigation of the flavonoidal constituents of the butanol fraction of the aqueous methanolic extract of Carrichteraannua seeds led to isolation and identification of a new flavonoidal glycosidenamed as quercetin 3-O-[(6-sinapoyl-b-glucopyranosyl)-(1;2)-b-arabinopyranosyl]-7-O-b-glucopyranoside 1, in addition to, quarecetin-3-O-glucoside 2, isorhamnetin-3-O-b-runtinoside3, and isorhamnetin4.Structures of the isolated compounds were established by UV, MS, and 1 H and 13 C NMR.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded60    
    Comments [Add]    
    Cited by others 2    

Recommend this journal