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ORIGINAL ARTICLE
Year : 2010  |  Volume : 2  |  Issue : 3  |  Page : 128-131

Analysis of antimicrobial, antifungal and antioxidant activities of Juniperus excelsa M. B subsp. Polycarpos (K. Koch) Takhtajan essential oil


1 Department of Pharmacognosy, Faculty of Pharmacy, Shiraz University of Medical Sciences, 71345-1583, Shiraz, Iran
2 Department of Biotechnology and Pharmaceutical Sciences Research Center, Faculty of Pharmacy, Shiraz University of Medical Sciences, 71345-1583, Shiraz, Iran
3 Department of Biochemistry, Faculty of Medicine, and Research Center for Molecular Medicine, Hormozgan University of Medical Sciences, 79149-64153, Bandar Abbas, Iran

Correspondence Address:
M R Moein
Department of Pharmacognosy and Pharmaceutical Sciences Research Center, Faculty of Pharmacy, Shiraz University of Medical Sciences, 71345-1583, Shiraz
Iran
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Source of Support: Shiraz University of Medical Sciences, Shiraz, Iran (grant 3258)., Conflict of Interest: None


DOI: 10.4103/0974-8490.65505

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Juniperus excelsa M.B subsp. Polycarpos (K.Koch), collected from south of Iran, was subjected to hydrodistillation using clevenger apparatus to obtain essential oil. The essential was analyzed by gas chromatography/mass spectrometry (GC/MS) and studied for antimicrobial, antifungal and antioxidant activities. The results indicated α-pinene (67.71%) as the major compound and α-cedral (11.5%), δ3-carene (5.19%) and limonene (4.41%) in moderate amounts. Antimicrobial tests were carried out using disk diffusion method, followed by the measurement of minimum inhibitory concentration (MIC). All the Gram positive and Gram negative bacteria were susceptible to essential oil. The oil showed radical scavenging and antioxidant effects.


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