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RESEARCH ARTICLE
Year : 2009  |  Volume : 1  |  Issue : 5  |  Page : 327-330

Comparative Study of Cuscuta reflexa and Cassytha filiformis for Diuretic Activity


1 Department of Pharmacognosy, National College of Pharmacy, Shimoga, India
2 Department of Pharmacology, National College of Pharmacy, Shimoga, India

Correspondence Address:
K K Hullatti
Department of Pharmacognosy, National College of Pharmacy, Shimoga
India
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Source of Support: None, Conflict of Interest: None


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Aqueous and alcoholic extract of Cuscuta reflexa and Cassytha filiformis were investigated for diuretic activity in Wister rats. The extracts were administered once orally at a dose of 300mg/kg. Frusemide (20mg/kg) was used as standard reference drug and normal saline (25 ml/kg) was used as control. Total urine volume and concentration of Na + , K + and Cl excreted in urine were estimated. Aqueous and alcoholic extract of Cuscuta reflexa and Cassytha filiformis exhibited significant diuretic activity and caused marked increase in Na + and K + excretion, when compared to saline treated controls. However the diuretic activity of Cassytha filiformis extract was higher than that of Cuscuta reflexa.


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