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RESEARCH ARTICLE
Year : 2009  |  Volume : 1  |  Issue : 4  |  Page : 172-174 Table of Contents     

Essential Oil Composition of the Dracocephalum moldavica L from Xinjiang in China


1 College of TCM, XinJiang Medical University, Urumqi-830011, XinJiang, China
2 College of Pharmacy, XinJiang Medical University, Urumqi-830011, XinJiang, China
3 Institute of Quality Testing of Xinjiang; Urumqi-830002, XinJiang, China

Date of Submission18-May-2009
Date of Decision02-Apr-2009
Date of Acceptance03-Jun-2009
Date of Web Publication2-Jan-2010

Correspondence Address:
Tian Shuge
College of TCM, XinJiang Medical University, Urumqi-830011, XinJiang
China
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Source of Support: None, Conflict of Interest: None


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   Abstract 

The essential oil of Dracocephalum moldavica L from Xinjiang in China was isolated by hydrodistillation in yield of 0.15 %(w/w). The chemical composition of the essential oil was analyzed by GC and GCMS. Fifty-one compounds accounting for 99.45% of the total oil were identified. The major components werea-Citral (32.55%), β-Citral (23.53%), Acetic acid, geranial ester(21.32%), Trans-Geraniol(3.38%), Nerolacetate(3.38%), Octane(2.14%), and 2,4,6-Trimethyl -3-cyclohexene-1-carboxaldehyde (1.3%). Monotenepers were the main group of compounds.

Keywords: Dracocephalum moldavica L, essential oil composition, GC-MS


How to cite this article:
Shuge T, Xiaoying Z, Fan Z, Dongqing A, Tao Y. Essential Oil Composition of the Dracocephalum moldavica L from Xinjiang in China. Phcog Res 2009;1:172-4

How to cite this URL:
Shuge T, Xiaoying Z, Fan Z, Dongqing A, Tao Y. Essential Oil Composition of the Dracocephalum moldavica L from Xinjiang in China. Phcog Res [serial online] 2009 [cited 2019 Aug 24];1:172-4. Available from: http://www.phcogres.com/text.asp?2009/1/4/172/58086


   Introduction Top


Dracocephalum moldavica L. is a perennial herb belonging to the Lamiaceae (Labiatae) family. is an annual herbaceous aromatic plant belonging to the family Lamiaceae (Labiatae). It is native to central Asia and is naturalized in eastern and central Europe [1] . In China, it is predominantly found in the north of the country, especially in XinJiang Province. This plant, with the common local name of Xiangqinglan or Uygur's name Badelajibuya, has been of interest to Uygur traditional medicine, especially in north XinJiang Province. It is used as a food ingredient, as a tea, as a herbal drug for its reputed medicinal properties, e.g. for the treatment of stomach and liver disorders, headaches and congestion [2],[3],[4] .


   Materials and Methods Top


Plant material

The aerial parts of Dracocephalum moldavica L growing Liyu mountain of Urumqi in Xinjiang were collected during flowering. Voucher specimens were deposited in Traditional Chinese Medicine College Museum of Chinese herbal samples of Xinjiang Medical University.

Preparation of extract

The sample was weighed (100g, 3times), then steam distilled with a Clevenger-type apparatus for 6 h; the oil was collected and dried over anhydrous sodium sulfate, then stored at 4°C until analyzed.

Gas Chromatography

GC-MS analyses were carried out using a Shimadzu QP-2010 GC-MS system operating in the EI mode at 70 eV with scanning from 41 to 450 amu at 0.5 s, using a DB-5 (30 m, 0.25 mm, film thickness 0.25μm) capillary column. The temperature program was 40-250°C at a rate of 5°C/min. Injector and transfer line temperatures were 250°C, the ion source temperature was 200°C. Helium was used as the carrier gas, flow rate 1 mL/min. Split ratio, 1:100.

Identification of the Components

The identification of the components was made by comparison of their retention time with respect to the n-alkane series (C6-C22) internal standards. The mass spectra and relative retention indices (RRI) were compared with those of commercial (NIST 05 and NIST 05 S). Area percentages were obtained from the TIC response without the use of an internal standard.


   Results and Discussion Top


The volatile light salmon pink oil (0.15% wt/wt) was obtained by hydrodistillation of whole grass and analyzed by GC-MS [Figure 1]. A total of 51 out of 54 compounds representing 99.45% of the oil was identified [Table 1]. The major components were α-Citral (32.55%), β-Citral (23.53%), Acetic acid, geranial ester (21.32%), Trans-Geraniol (3.38%), Nerol acetate (3.38%), Octane (2.14%), and 2, 4, 6-Trimethyl-3-cyclohexene-1-carboxaldehyde (1.3%). Monotenepers were the main group of compounds. Citral are known to be antibiotics [6] . The antifungal and bactericidal properties of Citral have been reported [7],[8] . Citral also is a new inducer of caspase-3 in tumor cell lines [9] . The high proportion of Citral in this plant could contribute to its medicinal properties. When the results of studies on literature values were compared with those of [Table 1], the oils showed differences and similarities. The reason for this variability can be understood if we take into account all the factors influencing the chemical composition of the oils, namely, climatic, seasonal, and geographic condition, harvest period, and distillation technique, among others.


   Acknowledgement Top


This work was supported by a grant from China, the Xinjiang Province Office of Science and Technology Funding (Grant NO:200821130).

 
   References Top

1.Index of Garden Plants. (Griffiths M, Macmillan Press Ltd, Lon­don, 1994) pp:866.  Back to cited text no. 1      
2.Pharmcography of Uygur. (LIU Y, SHAWUTI Y, Xinjiang People's Publishing House, Urumqi, Xinjiang, China, 1985) pp: 329-331  Back to cited text no. 2      
3.Standard of Medicine PRC.- Uygur Medicine Fascicule. (Chinese Pharmacopoeia Commission, Xinjiang People's Publishing House, Urumqi, Xinjiang, China, 1999) pp:73-74.  Back to cited text no. 3      
4.Flora Xinjianggensis. (Mijiti H, PAN X L, Xinjiang People's Pub­lishing House, Urumqi, Xinjiang, China, Tomus 4, 1992) pp:265-268  Back to cited text no. 4      
5.Standard of Uygur Medicine. (Department of Health of Xinjiang Uygur Autonomous Region, Xinjiang People's Publishing House, Urumqi, Xinjiang, China, 1993)pp:245-246  Back to cited text no. 5      
6.Stevens K. L., Jurd L., King A. D.Jr and Mihara K. The antimi­crobial activity of citral, Cellular and Molecular Life Sciences (CMLS), 27(5):600-602(1971).  Back to cited text no. 6      
7.KIM J. M., MARSHALL M. R., CORNELL J. A., PRESTON J. F., WEI C. I. Antibacterial activity of carvacrol, citral, and geraniol against Salmonella typhimurium in culture medium and on fish cubes, Journal of food science, 60(6):1364-1374(1995).  Back to cited text no. 7      
8.Onawunmi G. O. Evaluation of the antimicrobial activity of citral, Letters in Applied Microbiology, 19(3):105-108(2008).  Back to cited text no. 8      
9.DUDAI N., WEINSTEIN Y., Margalit K. R., RABINSKI T., Rivka O. Citral is a new inducer of caspase-3 in tumor cell lines, Planta medica, 71(5):484-488(2005).  Back to cited text no. 9      


    Figures

  [Figure 1]
 
 
    Tables

  [Table 1]



 

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