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RESEARCH ARTICLE
Year : 2009  |  Volume : 1  |  Issue : 3  |  Page : 125-129

Biological activity of Crambe orientalis L. growing in Iran


1 Department of Biology, University of Mohaghegh Ardabili, Ardabil, Iran
2 Depatrment of Animal Sciences, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran

Correspondence Address:
S M Razavi
Department of Biology, University of Mohaghegh Ardabili, Ardabil
Iran
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Source of Support: None, Conflict of Interest: None


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Crambe orientalis (Brassicaceae) is a perennial herb growing wild in Iran. Cytotoxic, antioxidant, antimicrobial and phttotoxic effects of the plant leaves extracts have been evaluated by MTT, DPPH, Disc diffusion and lettuce assays, respectively. Our results showed that dichloromethane and methanol extracts of the plant leaves exhibited high cytotoxic effects against Mc-Coy cell line with IC 50 , value of 659 and 432 μg/ml, respectively. The extracts indicated high antioxidant activity with RC 50 , value of 33.3 and 40.5 μg/ml, respectively. Methanol extract showed strong antibacterial activity against both gram-positive and gram-negative bacteria. All the extracts displayed significant allelopatic potential, as well as. It is assumed that biological activity of the plant may be related to presence of isothiocyanates in the plant leaves.


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